Systemic Expression of Notch Ligand Delta-Like 4 during Mycobacterial Infection Alters the T Cell Immune Response

The Notch ligand delta-like 4 (DLL4) is known to fine-tune the CD4(+) T cell cytokine response. DLL4 is expressed on the surface of antigen-presenting cells (APCs) in a MyD88-dependent manner. We found that DLL4 expression was upregulated on bone marrow progenitor cells and APCs in mice infected wit...

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Detalles Bibliográficos
Autores principales: Schaller, Matthew A., Allen, Ronald M., Kimura, Soichiro, Day, Cheryl L., Kunkel, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121470/
https://www.ncbi.nlm.nih.gov/pubmed/27933064
http://dx.doi.org/10.3389/fimmu.2016.00527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121470/
https://www.ncbi.nlm.nih.gov/pubmed/27933064
http://dx.doi.org/10.3389/fimmu.2016.00527

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