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Impact of Proton Pump Inhibitor Use on the Comparative Effectiveness and Safety of Prasugrel Versus Clopidogrel: Insights From the Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE‐ACS) Study

BACKGROUND: Proton pump inhibitors (PPIs) reduce gastrointestinal bleeding events but may alter clopidogrel metabolism. We sought to understand the comparative effectiveness and safety of prasugrel versus clopidogrel in the context of proton pump inhibitor (PPI) use. METHODS AND RESULTS: Using data...

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Detalles Bibliográficos
Autores principales: Jackson, Larry R., Peterson, Eric D., McCoy, Lisa A., Ju, Christine, Zettler, Marjorie, Baker, Brian A., Messenger, John C., Faries, Douglas E., Effron, Mark B., Cohen, David J., Wang, Tracy Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121485/
https://www.ncbi.nlm.nih.gov/pubmed/27792656
http://dx.doi.org/10.1161/JAHA.116.003824