Sulfur Dioxide Protects Against Collagen Accumulation in Pulmonary Artery in Association With Downregulation of the Transforming Growth Factor β1/Smad Pathway in Pulmonary Hypertensive Rats

BACKGROUND: We aimed to explore the role of endogenous sulfur dioxide (SO (2)) in pulmonary vascular collagen remodeling induced by monocrotaline and its mechanisms. METHODS AND RESULTS: A rat model of monocrotaline‐induced pulmonary vascular collagen remodeling was developed and administered with l...

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Detalles Bibliográficos
Autores principales: Yu, Wen, Liu, Die, Liang, Chen, Ochs, Todd, Chen, Stella, Chen, Selena, Du, Shuxu, Tang, Chaoshu, Huang, Yaqian, Du, Junbao, Jin, Hongfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121494/
https://www.ncbi.nlm.nih.gov/pubmed/27792648
http://dx.doi.org/10.1161/JAHA.116.003910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121494/
https://www.ncbi.nlm.nih.gov/pubmed/27792648
http://dx.doi.org/10.1161/JAHA.116.003910

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