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Sulfur Dioxide Protects Against Collagen Accumulation in Pulmonary Artery in Association With Downregulation of the Transforming Growth Factor β1/Smad Pathway in Pulmonary Hypertensive Rats
BACKGROUND: We aimed to explore the role of endogenous sulfur dioxide (SO (2)) in pulmonary vascular collagen remodeling induced by monocrotaline and its mechanisms. METHODS AND RESULTS: A rat model of monocrotaline‐induced pulmonary vascular collagen remodeling was developed and administered with l...
Autores principales: | Yu, Wen, Liu, Die, Liang, Chen, Ochs, Todd, Chen, Stella, Chen, Selena, Du, Shuxu, Tang, Chaoshu, Huang, Yaqian, Du, Junbao, Jin, Hongfang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121494/ https://www.ncbi.nlm.nih.gov/pubmed/27792648 http://dx.doi.org/10.1161/JAHA.116.003910 |
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