Chemerin Elicits Potent Constrictor Actions via Chemokine‐Like Receptor 1 (CMKLR1), not G‐Protein‐Coupled Receptor 1 (GPR1), in Human and Rat Vasculature

BACKGROUND: Circulating levels of chemerin are significantly higher in hypertensive patients and positively correlate with blood pressure. Chemerin activates chemokine‐like receptor 1 (CMKLR1 or ChemR23) and is proposed to activate the “orphan” G‐protein‐coupled receptor 1 (GPR1), which has been lin...

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Detalles Bibliográficos
Autores principales: Kennedy, Amanda J., Yang, Peiran, Read, Cai, Kuc, Rhoda E., Yang, Lucy, Taylor, Emily J. A., Taylor, Colin W., Maguire, Janet J., Davenport, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121526/
https://www.ncbi.nlm.nih.gov/pubmed/27742615
http://dx.doi.org/10.1161/JAHA.116.004421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121526/
https://www.ncbi.nlm.nih.gov/pubmed/27742615
http://dx.doi.org/10.1161/JAHA.116.004421

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