Antibody-antigen kinetics constrain intracellular humoral immunity

During infection with non-enveloped viruses, antibodies stimulate immunity from inside cells by activating the cytosolic Fc receptor TRIM21. This intracellular humoral response relies on opsonized viral particles reaching the cytosol intact but the antigenic and kinetic constraints involved are unkn...

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Detalles Bibliográficos
Autores principales: Bottermann, Maria, Lode, Heidrun Elisabeth, Watkinson, Ruth E., Foss, Stian, Sandlie, Inger, Andersen, Jan Terje, James, Leo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121590/
https://www.ncbi.nlm.nih.gov/pubmed/27881870
http://dx.doi.org/10.1038/srep37457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121590/
https://www.ncbi.nlm.nih.gov/pubmed/27881870
http://dx.doi.org/10.1038/srep37457

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