Inhibition of lysophosphatidic acid receptors 1 and 3 attenuates atherosclerosis development in LDL-receptor deficient mice

Lysophosphatidic acid (LPA) is a natural lysophospholipid present at high concentrations within lipid-rich atherosclerotic plaques. Upon local accumulation in the damaged vessels, LPA can act as a potent activator for various types of immune cells through its specific membrane receptors LPA(1/3.) LP...

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Detalles Bibliográficos
Autores principales: Kritikou, Eva, van Puijvelde, Gijs H. M., van der Heijden, Thomas, van Santbrink, Peter J., Swart, Maarten, Schaftenaar, Frank H., Kröner, Mara J., Kuiper, Johan, Bot, Ilze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121611/
https://www.ncbi.nlm.nih.gov/pubmed/27883026
http://dx.doi.org/10.1038/srep37585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121611/
https://www.ncbi.nlm.nih.gov/pubmed/27883026
http://dx.doi.org/10.1038/srep37585

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