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Nucleoside-Diphosphate-Kinase of P. gingivalis is Secreted from Epithelial Cells In the Absence of a Leader Sequence Through a Pannexin-1 Interactome

Nucleoside-diphosphate-kinases (NDKs) are leaderless, multifunctional enzymes. The mode(s) of NDK secretion is currently undefined, while extracellular translocation of bacterial NDKs is critical for avoidance of host pathogen clearance by opportunistic pathogens such as Porphyromonas gingivalis. P....

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Detalles Bibliográficos
Autores principales: Atanasova, Kalina, Lee, Jungnam, Roberts, JoAnn, Lee, Kyulim, Ojcius, David M, Yilmaz, Özlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121656/
https://www.ncbi.nlm.nih.gov/pubmed/27883084
http://dx.doi.org/10.1038/srep37643