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Mint3/Apba3 depletion ameliorates severe murine influenza pneumonia and macrophage cytokine production in response to the influenza virus

Influenza virus (IFV) infection is a common cause of severe pneumonia. Studies have suggested that excessive activation of the host immune system including macrophages is responsible for the severe pathologies mediated by IFV infection. Here, we focused on the X11 protein family member Mint3/Apba3,...

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Detalles Bibliográficos
Autores principales: Uematsu, Takayuki, Fujita, Tomoko, Nakaoka, Hiroki J., Hara, Toshiro, Kobayashi, Noritada, Murakami, Yoshinori, Seiki, Motoharu, Sakamoto, Takeharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121658/
https://www.ncbi.nlm.nih.gov/pubmed/27883071
http://dx.doi.org/10.1038/srep37815