Impaired Endothelial Nitric Oxide Synthase Homodimer Formation Triggers Development of Transplant Vasculopathy - Insights from a Murine Aortic Transplantation Model

Transplant vasculopathy (TV) represents a major obstacle to long-term graft survival and correlates with severity of ischemia reperfusion injury (IRI). Donor administration of the nitric oxide synthases (NOS) co-factor tetrahydrobiopterin has been shown to prevent IRI. Herein, we analysed whether te...

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Detalles Bibliográficos
Autores principales: Oberhuber, Rupert, Riede, Gregor, Cardini, Benno, Bernhard, David, Messner, Barbara, Watschinger, Katrin, Steger, Christina, Brandacher, Gerald, Pratschke, Johann, Golderer, Georg, Werner, Ernst R., Maglione, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121662/
https://www.ncbi.nlm.nih.gov/pubmed/27883078
http://dx.doi.org/10.1038/srep37917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121662/
https://www.ncbi.nlm.nih.gov/pubmed/27883078
http://dx.doi.org/10.1038/srep37917

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