Cargando…

Impaired Endothelial Nitric Oxide Synthase Homodimer Formation Triggers Development of Transplant Vasculopathy - Insights from a Murine Aortic Transplantation Model

Transplant vasculopathy (TV) represents a major obstacle to long-term graft survival and correlates with severity of ischemia reperfusion injury (IRI). Donor administration of the nitric oxide synthases (NOS) co-factor tetrahydrobiopterin has been shown to prevent IRI. Herein, we analysed whether te...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oberhuber, Rupert, Riede, Gregor, Cardini, Benno, Bernhard, David, Messner, Barbara, Watschinger, Katrin, Steger, Christina, Brandacher, Gerald, Pratschke, Johann, Golderer, Georg, Werner, Ernst R., Maglione, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121662/ https://www.ncbi.nlm.nih.gov/pubmed/27883078 http://dx.doi.org/10.1038/srep37917

Ejemplares similares

Crucial Role for Neuronal Nitric Oxide Synthase in Early Microcirculatory Derangement and Recipient Survival following Murine Pancreas Transplantation
por: Cardini, Benno, et al.
Publicado: (2014)

Prevention of lethal murine pancreas ischemia reperfusion injury is specific for tetrahydrobiopterin
por: Maglione, Manuel, et al.
Publicado: (2012)

Sodium Sulfite Exacerbates Allograft Vasculopathy and Affects Tryptophan Breakdown in Murine Heterotopic Aortic Transplantation
por: Sucher, Robert, et al.
Publicado: (2019)

Mouse Model for Pancreas Transplantation Using a Modified Cuff Technique
por: Cardini, Benno, et al.
Publicado: (2017)

Post-Transplant Malignancies following Pancreas Transplantation: Incidence and Implications on Long-Term Outcome from a Single-Center Perspective
por: Krendl, Felix J., et al.
Publicado: (2021)

Physarum nitric oxide synthases: genomic structures and enzymology of recombinant proteins
por: Messner, Simon, et al.
Publicado: (2009)

Sex matching does not impact the outcome after simultaneous pancreas‐kidney transplantation
por: Messner, Franka, et al.
Publicado: (2019)

Perioperative Perfusion of Allografts with Anti-Human T-lymphocyte Globulin Does Not Improve Outcome Post Liver Transplantation—A Randomized Placebo-Controlled Trial
por: Ritschl, Paul Viktor, et al.
Publicado: (2021)

Liver Transplantation in Recipients With a Positive Crossmatch: A Retrospective Single-Center Match-Pair Analysis
por: Krendl, Felix J., et al.
Publicado: (2023)

Donor cardiac arrest and cardiopulmonary resuscitation: impact on outcomes after simultaneous pancreas–kidney transplantation – a retrospective study
por: Messner, Franka, et al.
Publicado: (2020)

Graft Pre-conditioning by Peri-Operative Perfusion of Kidney Allografts With Rabbit Anti-human T-lymphocyte Globulin Results in Improved Kidney Graft Function in the Early Post-transplantation Period—a Prospective, Randomized Placebo-Controlled Trial
por: Ritschl, Paul V., et al.
Publicado: (2018)

Transplanting Marginal Organs in the Era of Modern Machine Perfusion and Advanced Organ Monitoring
por: Resch, Thomas, et al.
Publicado: (2020)

Good Results with Individually Adapted Long-Term Immunosuppression Following Alemtuzumab Versus ATG Induction Therapy in Combined Kidney-Pancreas Transplantation: A Single-Center Report
por: Bösmüller, Claudia, et al.
Publicado: (2019)

Reassessment of Relevance and Predictive Value of Parameters Indicating Early Graft Dysfunction in Liver Transplantation: AST Is a Weak, but Bilirubin and INR Strong Predictors of Mortality
por: Fodor, Margot, et al.
Publicado: (2021)

Biochemical Characterization of AGMO Variants Implicated in Relapses in Visceral Leishmaniasis
por: Watschinger, Katrin, et al.
Publicado: (2018)

Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report
por: Bogensperger, Christina, et al.
Publicado: (2020)

Monitoring of fatty aldehyde dehydrogenase by formation of pyrenedecanoic acid from pyrenedecanal
por: Keller, Markus A., et al.
Publicado: (2010)

Good Long-term Results Following Simultaneous Pancreas-kidney Transplantation in a 69-y-old Recipient: A Case Report
por: Bösmüller, Claudia, et al.
Publicado: (2021)

Treatment With Tetrahydrobiopterin Overcomes Brain Death–Associated Injury in a Murine Model of Pancreas Transplantation
por: Oberhuber, R., et al.
Publicado: (2015)

The influence of liver transplantation on the interplay between gut microbiome and bile acid homeostasis in children with biliary atresia
por: Waldner, Birgit, et al.
Publicado: (2023)

A Large-Scale Bank of Organ Donor Bone Marrow and Matched Mesenchymal Stem Cells for Promoting Immunomodulation and Transplant Tolerance
por: Johnstone, Brian H., et al.
Publicado: (2021)

Outcomes of pancreas retransplantation in patients with pancreas graft failure
por: Gasteiger, S., et al.
Publicado: (2018)

Cardiac allograft vasculopathy in Dutch heart transplant recipients
por: Galli, G., et al.
Publicado: (2016)

Triptolide Attenuates Transplant Vasculopathy Through Multiple Pathways
por: Luo, Zihuan, et al.
Publicado: (2020)

Bioenergetic and Cytokine Profiling May Help to Rescue More DCD Livers for Transplantation
por: Hofmann, Julia, et al.
Publicado: (2023)

Endothelial Nitric Oxide Synthase Gene T-786C Polymorphism in Renal Transplant Recipients
por: Azarpira, N., et al.
Publicado: (2011)

Successful Combined Pancreas Fourth-Kidney Third and Pancreas Third-Kidney Second Transplantation: A Case Report
por: Bösmüller, Claudia, et al.
Publicado: (2015)

Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth
por: Costantino, Luca, et al.
Publicado: (2022)

Insights from Computational Modeling in Inflammation and Acute Rejection in Limb Transplantation
por: Wolfram, Dolores, et al.
Publicado: (2014)

Far-Infrared Therapy Decreases Orthotopic Allograft Transplantation Vasculopathy
por: Lin, Yi-Wen, et al.
Publicado: (2022)

Factors associated with cardiac allograft vasculopathy after heart transplantation
por: Szczurek-Wasilewicz, Wioletta, et al.
Publicado: (2022)

The challenge to detect heart transplant rejection and transplant vasculopathy non-invasively - a pilot study
por: Usta, Engin, et al.
Publicado: (2009)

Differential depletion of total T cells and regulatory T cells and prolonged allotransplant survival in CD3Ɛ humanized mice treated with polyclonal anti human thymocyte globulin
por: Buszko, Maja, et al.
Publicado: (2017)

Abstract QS37: Induction Of Delayed Immune Tolerance After Reconstructive Transplantation By Combining Donor Bone Marrow Transplantation And High-dose Cyclophosphamide Treatment
por: GUO, YINAN, et al.
Publicado: (2019)

A novel assay for the introduction of the vinyl ether double bond into plasmalogens using pyrene-labeled substrates
por: Werner, Ernst R., et al.
Publicado: (2018)

Multiple Shades of Gray—Macrophages in Acute Allograft Rejection
por: Lackner, Katharina, et al.
Publicado: (2023)

Ex Vivo Mesenchymal Stem Cell Therapy to Regenerate Machine Perfused Organs
por: Bogensperger, Christina, et al.
Publicado: (2021)

Studying fatty aldehyde metabolism in living cells with pyrene-labeled compounds
por: Keller, Markus A., et al.
Publicado: (2012)

Single Center, Propensity Score Matching Analysis of Different Reconstruction Techniques following Pancreatoduodenectomy
por: Bellotti, Ruben, et al.
Publicado: (2023)

Ischemia-Reperfusion Injury Accelerates Human Antibody-Mediated Transplant Vasculopathy
por: Goto, Ryoichi, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_bs6valhfrbkl2k8ie2062hgv5t