Direct electrical control of IgG conformation and functional activity at surfaces

We have devised a supramolecular edifice involving His-tagged protein A and antibodies to yield surface immobilized, uniformly oriented, IgG-type, antibody layers with F(ab) fragments exposed off an electrode surface. We demonstrate here that we can affect the conformation of IgGs, likely pushing/pu...

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Detalles Bibliográficos
Autores principales: Ghisellini, Paola, Caiazzo, Marialuisa, Alessandrini, Andrea, Eggenhöffner, Roberto, Vassalli, Massimo, Facci, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121884/
https://www.ncbi.nlm.nih.gov/pubmed/27883075
http://dx.doi.org/10.1038/srep37779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121884/
https://www.ncbi.nlm.nih.gov/pubmed/27883075
http://dx.doi.org/10.1038/srep37779

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