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Direct electrical control of IgG conformation and functional activity at surfaces
We have devised a supramolecular edifice involving His-tagged protein A and antibodies to yield surface immobilized, uniformly oriented, IgG-type, antibody layers with F(ab) fragments exposed off an electrode surface. We demonstrate here that we can affect the conformation of IgGs, likely pushing/pu...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121884/ https://www.ncbi.nlm.nih.gov/pubmed/27883075 http://dx.doi.org/10.1038/srep37779 |