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Existence of mutations in the homeodomain-encoding region of NKX2.5 gene in Iranian patients with tetralogy of Fallot

BACKGROUND: Tetralogy of Fallot (TOF), the most common cyanotic heart defect and one of the most common congenital heart diseases, occurs mostly sporadically and nonsyndromically. The underlying molecular genetic mechanism is not known. Therefore, the existence of mutations in the homeodomain-encodi...

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Detalles Bibliográficos
Autores principales: Kheirollahi, Majid, Khosravi, Fereshteh, Ashouri, Saeideh, Ahmadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122105/
https://www.ncbi.nlm.nih.gov/pubmed/27904570
http://dx.doi.org/10.4103/1735-1995.179893