Augmentation of histone deacetylase 3 (HDAC3) epigenetic signature at the interface of proinflammation and insulin resistance in patients with type 2 diabetes

BACKGROUND: A role of proinflammation has been implicated in the pathogenesis of diabetes, but the up-stream regulatory signals and molecular signatures are poorly understood. While histone modifications such as changes in histone deacetylase (HDAC) are emerging as novel epigenetic biomarkers, there...

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Detalles Bibliográficos
Autores principales: Sathishkumar, Chandrakumar, Prabu, Paramasivam, Balakumar, Mahalingam, Lenin, Raji, Prabhu, Durai, Anjana, Ranjith Mohan, Mohan, Viswanathan, Balasubramanyam, Muthuswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122206/
https://www.ncbi.nlm.nih.gov/pubmed/27904654
http://dx.doi.org/10.1186/s13148-016-0293-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122206/
https://www.ncbi.nlm.nih.gov/pubmed/27904654
http://dx.doi.org/10.1186/s13148-016-0293-3

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