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The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons

Transforming growth factor β (TGFβ)-mediated anti-proliferative and differentiating effects promote neuronal differentiation during embryonic central nervous system development. TGFβ downstream signals, composed of activated SMAD2/3, SMAD4 and a FOXO family member, promote the expression of cyclin-d...

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Detalles Bibliográficos
Autores principales: Vezzali, Riccardo, Weise, Stefan Christopher, Hellbach, Nicole, Machado, Venissa, Heidrich, Stefanie, Vogel, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122323/
https://www.ncbi.nlm.nih.gov/pubmed/27224923
http://dx.doi.org/10.18632/oncotarget.9545