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c-Src/Cav1-dependent activation of the EGFR by Dsg2

The desmosomal cadherin, desmoglein 2 (Dsg2), is deregulated in a variety of human cancers including those of the skin. When ectopically expressed in the epidermis of transgenic mice, Dsg2 activates multiple mitogenic signaling pathways and increases susceptibility to tumorigenesis. However, the mol...

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Detalles Bibliográficos
Autores principales: Overmiller, Andrew M., McGuinn, Kathleen P., Roberts, Brett J., Cooper, Felicia, Brennan-Crispi, Donna M., Deguchi, Takahiro, Peltonen, Sirkku, James K., Wahl, Mahoney, M? G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122330/
https://www.ncbi.nlm.nih.gov/pubmed/26918609
http://dx.doi.org/10.18632/oncotarget.7675