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Lysophosphatidic acid stimulates epithelial to mesenchymal transition marker Slug/Snail2 in ovarian cancer cells via Gαi2, Src, and HIF1α signaling nexus

Recent studies have identified a critical role for lysophosphatidic acid (LPA) in the progression of ovarian cancer. Using a transcription factor activation reporter array, which analyzes 45 distinct transcription factors, it has been observed that LPA observed robustly activates the transcription f...

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Detalles Bibliográficos
Autores principales: Ha, Ji Hee, Ward, Jeremy D., Radhakrishnan, Rangasudhagar, Jayaraman, Muralidharan, Song, Yong Sang, Dhanasekaran, Danny N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122340/
https://www.ncbi.nlm.nih.gov/pubmed/27166196
http://dx.doi.org/10.18632/oncotarget.9224