Blockade of MCP-1/CCR4 signaling-induced recruitment of activated regulatory cells evokes an antitumor immune response in head and neck squamous cell carcinoma

FoxP3(+) regulatory T (Treg) cells have diverse functions in the suppression of antitumor immunity. We show that FoxP3(hi)CD45RA(−)CD4(+) Treg cells [activated Treg (aTreg) cells] are the predominant cell population among tumor-infiltrating FoxP3(+) T cells, and that high aTreg cell-infiltrating con...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Wei, Li, Wei-Jin, Wei, Fan-Qin, Wong, Thian-Sze, Lei, Wen-Bin, Zhu, Xiao-Lin, Li, Jian, Wen, Wei-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122343/
https://www.ncbi.nlm.nih.gov/pubmed/27177223
http://dx.doi.org/10.18632/oncotarget.9265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122343/
https://www.ncbi.nlm.nih.gov/pubmed/27177223
http://dx.doi.org/10.18632/oncotarget.9265

Ejemplares similares