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Rs2853677 modulates Snail1 binding to the TERT enhancer and affects lung adenocarcinoma susceptibility

Genome wide association studies (GWAS) have shown that SNPs in non-coding regions are associated with inherited susceptibility to cancer. The effect of one single SNP, however, is weak. To identify potential co-factors of SNPs, we investigated the underlying mechanism by which SNPs affect lung cance...

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Detalles Bibliográficos
Autores principales: Li, Xiaoting, Xu, Xing, Fang, Jiali, Wang, Lin, Mu, Yanchao, Zhang, Peng, Yao, Zhi, Ma, Zhenyi, Liu, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122352/
https://www.ncbi.nlm.nih.gov/pubmed/27191258
http://dx.doi.org/10.18632/oncotarget.9339