DNA demethylating agent decitabine broadens the peripheral T cell receptor repertoire

PURPOSE: Decitabine, a promising epi-immunotherapeutic agent has shown clinical responses in solid tumor patients, while the anti-tumor mechanisms were unclear. We aimed to investigate the immunomodulatory effect of decitabine in peripheral T cells. EXPERIMENTAL DESIGN: We applied next-generation se...

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Detalles Bibliográficos
Autores principales: Nie, Jing, Zhang, Yan, Li, Xiang, Chen, Meixia, Liu, Chuanjie, Han, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122357/
https://www.ncbi.nlm.nih.gov/pubmed/27191266
http://dx.doi.org/10.18632/oncotarget.9352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122357/
https://www.ncbi.nlm.nih.gov/pubmed/27191266
http://dx.doi.org/10.18632/oncotarget.9352

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