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Fucoidan inhibits lymphangiogenesis by downregulating the expression of VEGFR3 and PROX1 in human lymphatic endothelial cells

Lymphangiogenesis is one of the promoters of tumor lymphatic metastasis. Fucoidan which is a fucose-enriched sulfated polysaccharide has effect on various pharmacological activities including anti-metastasis activity. However, the inhibitory effect of fucoidan on lymphangiogenesis remains unclear. H...

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Detalles Bibliográficos
Autores principales: Yang, Yazong, Gao, Zixiang, Ma, Yanhong, Teng, Hongming, Liu, Zundong, Wei, Hengyun, Lu, Yanbing, Cheng, Xiaofang, Hou, Lin, Zou, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122369/
https://www.ncbi.nlm.nih.gov/pubmed/27203545
http://dx.doi.org/10.18632/oncotarget.9443