Cargando…
Fucoidan inhibits lymphangiogenesis by downregulating the expression of VEGFR3 and PROX1 in human lymphatic endothelial cells
Lymphangiogenesis is one of the promoters of tumor lymphatic metastasis. Fucoidan which is a fucose-enriched sulfated polysaccharide has effect on various pharmacological activities including anti-metastasis activity. However, the inhibitory effect of fucoidan on lymphangiogenesis remains unclear. H...
Autores principales: | Yang, Yazong, Gao, Zixiang, Ma, Yanhong, Teng, Hongming, Liu, Zundong, Wei, Hengyun, Lu, Yanbing, Cheng, Xiaofang, Hou, Lin, Zou, Xiangyang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122369/ https://www.ncbi.nlm.nih.gov/pubmed/27203545 http://dx.doi.org/10.18632/oncotarget.9443 |
Ejemplares similares
-
Fucoidan Suppresses Hypoxia-Induced Lymphangiogenesis and Lymphatic Metastasis in Mouse Hepatocarcinoma
por: Teng, Hongming, et al.
Publicado: (2015) -
Protective Effects of Fucoidan on Aβ25–35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice
por: Wei, Hengyun, et al.
Publicado: (2017) -
The Prox1–Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors
por: Srinivasan, R. Sathish, et al.
Publicado: (2014) -
Exosomal circ_0026611 contributes to lymphangiogenesis by reducing PROX1 acetylation and ubiquitination in human lymphatic endothelial cells (HLECs)
por: Yao, Wenjian, et al.
Publicado: (2023) -
Expression of platelet-derived growth factor receptor β is maintained by Prox1 in lymphatic endothelial cells and is required for tumor lymphangiogenesis
por: Miyazaki, Hideki, et al.
Publicado: (2014)