Derivatives of 6-cinnamamido-quinoline-4-carboxamide impair lysosome function and induce apoptosis

Autophagy is a lysosomal degradative process that protects cancer cells from multiple types of stress. In this study, we synthesized a series of derivatives of 6-cinnamamido-quinoline-4-carboxamide (CiQ), and investigated their effects on the proliferation and autophagy of cancer cells in vitro. The...

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Detalles Bibliográficos
Autores principales: Kuo, Hsiao-Hui, Kakadiya, Rajesh, Wu, Yi-Chen, Su, Tsann-Long, Lee, Te-Chang, Lin, Yi-Wen, Yih, Ling-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122373/
https://www.ncbi.nlm.nih.gov/pubmed/27191263
http://dx.doi.org/10.18632/oncotarget.9348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122373/
https://www.ncbi.nlm.nih.gov/pubmed/27191263
http://dx.doi.org/10.18632/oncotarget.9348

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