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Phage display library selection of a hypoxia-binding scFv antibody for liver cancer metabolic marker discovery

Hypoxia, which is frequently observed in liver cancer and metastasis, influences tumor progression and resistance to therapy. Although hypoxia-associated biomarkers are of use in other cancers, none is recognized as a surrogate for hypoxia in liver cancer. In this study, we generated seven unique hu...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Zhang, Qing, Chen, Hang, Gao, Zhihui, Li, Yao, Sun, Zhongyuan, Xiang, Rong, Zhang, Sihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122375/
https://www.ncbi.nlm.nih.gov/pubmed/27203546
http://dx.doi.org/10.18632/oncotarget.9460