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Quantitation of TGF-β proteins in mouse tissues shows reciprocal changes in TGF-β1 and TGF-β3 in normal vs neoplastic mammary epithelium

Transforming growth factor-βs (TGF-βs) regulate tissue homeostasis, and their expression is perturbed in many diseases. The three isoforms (TGF-β1, -β2, and -β3) have similar bioactivities in vitro but show distinct activities in vivo. Little quantitative information exists for expression of TGF-β i...

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Detalles Bibliográficos
Autores principales: Flanders, Kathleen C., Yang, Yu-an, Herrmann, Michelle, Chen, JinQiu, Mendoza, Nerissa, Mirza, Amer M., Wakefield, Lalage M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122380/
https://www.ncbi.nlm.nih.gov/pubmed/27203217
http://dx.doi.org/10.18632/oncotarget.9416