Accumulation of RNA-dependent protein kinase (PKR) in the nuclei of lung cancer cells mediates radiation resistance

We have previously demonstrated that radiation induced cell death in PKR (−/−) deficient mouse embryo fibroblasts (MEFs) but not in PKR (+/+) wild type MEFs. Our study indicated that PKR can also be involved in survival pathways following radiation therapy through activation of the AKT survival path...

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Detalles Bibliográficos
Autores principales: Hao, Chuncheng, Shao, Ruping, Raju, Uma, Fang, Bingliang, Swisher, Stephen G., Pataer, Apar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122385/
https://www.ncbi.nlm.nih.gov/pubmed/27203671
http://dx.doi.org/10.18632/oncotarget.9428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122385/
https://www.ncbi.nlm.nih.gov/pubmed/27203671
http://dx.doi.org/10.18632/oncotarget.9428

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