Drug conjugated nanoparticles activated by cancer cell specific mRNA

We describe a customizable approach to cancer therapy in which a gold nanoparticle (Au-NP) delivers a drug that is selectively activated within the cancer cell by the presence of an mRNA unique to the cancer cell. Fundamental to this approach is the observation that the amount of drug released from...

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Detalles Bibliográficos
Autores principales: Gossai, Nathan P., Naumann, Jordan A., Li, Nan-Sheng, Zamora, Edward A., Gordon, David J., Piccirilli, Joseph A., Gordon, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122386/
https://www.ncbi.nlm.nih.gov/pubmed/27203672
http://dx.doi.org/10.18632/oncotarget.9430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122386/
https://www.ncbi.nlm.nih.gov/pubmed/27203672
http://dx.doi.org/10.18632/oncotarget.9430

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