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Drug conjugated nanoparticles activated by cancer cell specific mRNA
We describe a customizable approach to cancer therapy in which a gold nanoparticle (Au-NP) delivers a drug that is selectively activated within the cancer cell by the presence of an mRNA unique to the cancer cell. Fundamental to this approach is the observation that the amount of drug released from...
Autores principales: | Gossai, Nathan P., Naumann, Jordan A., Li, Nan-Sheng, Zamora, Edward A., Gordon, David J., Piccirilli, Joseph A., Gordon, Peter M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122386/ https://www.ncbi.nlm.nih.gov/pubmed/27203672 http://dx.doi.org/10.18632/oncotarget.9430 |
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