Aptamer-guided DNA tetrahedron as a novel targeted drug delivery system for MUC1-expressing breast cancer cells in vitro

Mucin 1 (MUC1) is an important molecular target for cancer treatment because it is overexpressed in most adenocarcinomas. In this study, a new MUC1-targeted drug delivery system was assembled using an aptamer (Apt) that could recognize MUC1 and a DNA tetrahedron (Td) that could carry doxorubicin (Do...

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Detalles Bibliográficos
Autores principales: Dai, Bindong, Hu, Yan, Duan, JinHong, Yang, Xian-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122387/
https://www.ncbi.nlm.nih.gov/pubmed/27203221
http://dx.doi.org/10.18632/oncotarget.9431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122387/
https://www.ncbi.nlm.nih.gov/pubmed/27203221
http://dx.doi.org/10.18632/oncotarget.9431

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