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Overexpression of EZH2 is associated with the poor prognosis in osteosarcoma and function analysis indicates a therapeutic potential

Osteosarcoma is a primary malignant bone tumor that has a poor prognosis due to local recurrence, metastasis, and chemotherapy resistance. Therefore, there is an urgent need to develop novel potential therapeutic targets for osteosarcoma. Enhancer of zeste homologue 2 (EZH2) is a member of the polyc...

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Detalles Bibliográficos
Autores principales: Sun, Ranran, Shen, Jacson, Gao, Yan, Zhou, Yubing, Yu, Zujiang, Hornicek, Francis, Kan, Quancheng, Duan, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122393/
https://www.ncbi.nlm.nih.gov/pubmed/27223261
http://dx.doi.org/10.18632/oncotarget.9518