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Utility of patient-derived lymphoblastoid cell lines as an ex vivo capecitabine sensitivity prediction model for breast cancer patients

Capecitabine is commonly used in treating breast cancer; however, therapeutic response varies among patients and there is no clinically validated model to predict individual outcomes. Here, we investigated whether drug sensitivity quantified in ex vivo patients' blood-derived cell lines can pre...

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Detalles Bibliográficos
Autores principales: Morrison, Gladys, Lenkala, Divya, LaCroix, Bonnie, Ziliak, Dana, Abramson, Vandana, Morrow, Phuong Khanh, Forero, Andres, Van Poznak, Catherine, Rugo, Hope S, Nanda, Rita, O'Donnell, Peter H., Huang, R. Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122395/
https://www.ncbi.nlm.nih.gov/pubmed/27224917
http://dx.doi.org/10.18632/oncotarget.9521