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Increased translocation of antigens to endosomes and TLR4 mediated endosomal recruitment of TAP contribute to nicotine augmented cross-presentation

Cross-presentation by dendritic cells (DCs) requires surface molecules such as lectin, CD40, langerin, heat shock protein, mannose receptor, mediated endocytosis, the endosomal translocation of internalized antigen, and the relocation of transporter associated with antigen processing (TAP). Although...

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Detalles Bibliográficos
Autores principales: Wang, Yan Yan, Hu, Chun Fang, Li, Juan, You, Xiang, Gao, Feng Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122403/
https://www.ncbi.nlm.nih.gov/pubmed/27224911
http://dx.doi.org/10.18632/oncotarget.9498