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Selective antitumor activity of roscovitine in head and neck cancer

Radiation and chemotherapy that are commonly used to treat human cancers damage cellular DNA. DNA damage appears to be more toxic to cancer cells than normal cells, most likely due to deregulated checkpoint activation and/or deficiency in DNA repair pathways that are characteristics of many tumors....

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Detalles Bibliográficos
Autores principales: Gary, Cyril, Hajek, Michael, Biktasova, Asel, Bellinger, Gary, Yarbrough, Wendell G., Issaeva, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122414/
https://www.ncbi.nlm.nih.gov/pubmed/27233076
http://dx.doi.org/10.18632/oncotarget.9560