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Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells
Prion protein (PrP(C)) is a cell surface glycoprotein whose misfolding is responsible for prion diseases. Although its physiological role is not completely defined, several lines of evidence propose that PrP(C) is involved in self-renewal, pluripotency gene expression, proliferation and differentiat...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122417/ https://www.ncbi.nlm.nih.gov/pubmed/27229535 http://dx.doi.org/10.18632/oncotarget.9575 |