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Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells

Prion protein (PrP(C)) is a cell surface glycoprotein whose misfolding is responsible for prion diseases. Although its physiological role is not completely defined, several lines of evidence propose that PrP(C) is involved in self-renewal, pluripotency gene expression, proliferation and differentiat...

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Detalles Bibliográficos
Autores principales: Corsaro, Alessandro, Bajetto, Adriana, Thellung, Stefano, Begani, Giulia, Villa, Valentina, Nizzari, Mario, Pattarozzi, Alessandra, Solari, Agnese, Gatti, Monica, Pagano, Aldo, Würth, Roberto, Daga, Antonio, Barbieri, Federica, Florio, Tullio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122417/
https://www.ncbi.nlm.nih.gov/pubmed/27229535
http://dx.doi.org/10.18632/oncotarget.9575