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Exosomal cancer immunotherapy is independent of MHC molecules on exosomes

Peptide-loaded exosomes are promising cancer treatment vehicles; however, moderate T cell responses in human clinical trials indicate a need to further understand exosome-induced immunity. We previously demonstrated that antigen-loaded exosomes carry whole protein antigens and require B cells for in...

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Detalles Bibliográficos
Autores principales: Hiltbrunner, Stefanie, Larssen, Pia, Eldh, Maria, Martinez-Bravo, Maria-Jose, Wagner, Arnika K., Karlsson, Mikael C.I., Gabrielsson, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122422/
https://www.ncbi.nlm.nih.gov/pubmed/27231849
http://dx.doi.org/10.18632/oncotarget.9585