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BCL-W is a regulator of microtubule inhibitor-induced mitotic cell death

Microtubule inhibitors including taxanes and vinca alkaloids are among the most widely used anticancer agents. Disrupting the microtubules activates the spindle-assembly checkpoint and traps cells in mitosis. Whether cells subsequently undergo mitotic cell death is an important factor for the effect...

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Detalles Bibliográficos
Autores principales: Huang, Shan, Tang, Rui, Randy, Y.C. Poon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122423/
https://www.ncbi.nlm.nih.gov/pubmed/27231850
http://dx.doi.org/10.18632/oncotarget.9586