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Nuclear p16INK4a expression predicts enhanced radiation response in head and neck cancers

Immunohistochemistry analysis of p16INK4a in head and neck squamous cell carcinomas (HNSCC) tumor samples revealed that 28% of tumors showed nuclear/cytoplasmic p16INK4a localization, while 37% of tumors had cytoplasmic p16INK4a. Our previous study showed that p16INK4a inhibits the DNA repair respon...

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Detalles Bibliográficos
Autores principales: Dok, Rüveyda, Asbagh, Layka Abbasi, Van Limbergen, Evert Jan, Sablina, Anna, Nuyts, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122429/
https://www.ncbi.nlm.nih.gov/pubmed/27246975
http://dx.doi.org/10.18632/oncotarget.9609