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Technetium-99m-labeled rituximab for use as a specific tracer of sentinel lymph node biopsy: a translational research study

PURPOSE: We aimed to develop and translate a CD20-antigen-targeted radiopharmaceutical, Technetium-99 m-labeled ((99m)Tc) rituximab, for sentinel lymph node (SLN) detection. METHODS: (99m)Tc-rituximab was synthesized and tested for stability in human serum. The binding affinity to CD20 was evaluated...

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Detalles Bibliográficos
Autores principales: Wang, Xuejuan, Yang, Zhi, Lin, Baohe, Zhang, Yan, Zhai, Shizhen, Zhao, Qichao, Xie, Qing, Liu, Fei, Han, Xuedi, Li, Jinfeng, Ouyang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122431/
https://www.ncbi.nlm.nih.gov/pubmed/27246977
http://dx.doi.org/10.18632/oncotarget.9614