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Technetium-99m-labeled rituximab for use as a specific tracer of sentinel lymph node biopsy: a translational research study
PURPOSE: We aimed to develop and translate a CD20-antigen-targeted radiopharmaceutical, Technetium-99 m-labeled ((99m)Tc) rituximab, for sentinel lymph node (SLN) detection. METHODS: (99m)Tc-rituximab was synthesized and tested for stability in human serum. The binding affinity to CD20 was evaluated...
Autores principales: | Wang, Xuejuan, Yang, Zhi, Lin, Baohe, Zhang, Yan, Zhai, Shizhen, Zhao, Qichao, Xie, Qing, Liu, Fei, Han, Xuedi, Li, Jinfeng, Ouyang, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122431/ https://www.ncbi.nlm.nih.gov/pubmed/27246977 http://dx.doi.org/10.18632/oncotarget.9614 |
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