Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3'-end processing

The balance between self-renewal and differentiation of neural progenitor cells (NPCs) dictates neurogenesis and proper brain development. We found that the RNA- binding protein Sam68 (Khdrbs1) is strongly expressed in neurogenic areas of the neocortex and supports the self-renewing potential of mou...

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Detalles Bibliográficos
Autores principales: La Rosa, Piergiorgio, Bielli, Pamela, Compagnucci, Claudia, Cesari, Eleonora, Volpe, Elisabetta, Farioli Vecchioli, Stefano, Sette, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122457/
https://www.ncbi.nlm.nih.gov/pubmed/27845622
http://dx.doi.org/10.7554/eLife.20750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122457/
https://www.ncbi.nlm.nih.gov/pubmed/27845622
http://dx.doi.org/10.7554/eLife.20750

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