Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism

Neuroligins are postsynaptic cell-adhesion molecules implicated in autism and other neuropsychiatric disorders. Despite extensive work, the role of neuroligins in synapse function and plasticity, especially NMDA receptor (NMDAR)-dependent LTP, remains unclear. To establish which synaptic functions u...

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Detalles Bibliográficos
Autores principales: Jiang, Man, Polepalli, Jai, Chen, Lulu Y., Zhang, Bo, Südhof, Thomas C., Malenka, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122464/
https://www.ncbi.nlm.nih.gov/pubmed/27217145
http://dx.doi.org/10.1038/mp.2016.80

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122464/
https://www.ncbi.nlm.nih.gov/pubmed/27217145
http://dx.doi.org/10.1038/mp.2016.80

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