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Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism

Neuroligins are postsynaptic cell-adhesion molecules implicated in autism and other neuropsychiatric disorders. Despite extensive work, the role of neuroligins in synapse function and plasticity, especially NMDA receptor (NMDAR)-dependent LTP, remains unclear. To establish which synaptic functions u...

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Detalles Bibliográficos
Autores principales:	Jiang, Man, Polepalli, Jai, Chen, Lulu Y., Zhang, Bo, Südhof, Thomas C., Malenka, Robert C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122464/ https://www.ncbi.nlm.nih.gov/pubmed/27217145 http://dx.doi.org/10.1038/mp.2016.80

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