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Current Challenges and Limitations in Antibody-Based Detection of Citrullinated Histones

Studies on NETosis demand reliable and convenient markers to monitor the progress of this form of cell death. Because a determining step in the release of nuclear chromatin NETs requires the conversion of arginine residues to citrulline residues in histones by peptidylarginine deiminase, citrullinat...

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Detalles Bibliográficos
Autores principales: Neeli, Indira, Radic, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122592/
https://www.ncbi.nlm.nih.gov/pubmed/27933065
http://dx.doi.org/10.3389/fimmu.2016.00528