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Peptide IDR-1002 Inhibits NF-κB Nuclear Translocation by Inhibition of IκBα Degradation and Activates p38/ERK1/2–MSK1-Dependent CREB Phosphorylation in Macrophages Stimulated with Lipopolysaccharide

The inflammatory response is a critical molecular defense mechanism of the innate immune system that mediates the elimination of disease-causing bacteria. Repair of the damaged tissue, and the reestablishment of homeostasis, must be accomplished after elimination of the pathogen. The innate defense...

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Detalles Bibliográficos
Autores principales: Huante-Mendoza, Alejandro, Silva-García, Octavio, Oviedo-Boyso, Javier, Hancock, Robert E. W., Baizabal-Aguirre, Víctor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122595/
https://www.ncbi.nlm.nih.gov/pubmed/27933067
http://dx.doi.org/10.3389/fimmu.2016.00533