Cargando…

Peptide IDR-1002 Inhibits NF-κB Nuclear Translocation by Inhibition of IκBα Degradation and Activates p38/ERK1/2–MSK1-Dependent CREB Phosphorylation in Macrophages Stimulated with Lipopolysaccharide

The inflammatory response is a critical molecular defense mechanism of the innate immune system that mediates the elimination of disease-causing bacteria. Repair of the damaged tissue, and the reestablishment of homeostasis, must be accomplished after elimination of the pathogen. The innate defense...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huante-Mendoza, Alejandro, Silva-García, Octavio, Oviedo-Boyso, Javier, Hancock, Robert E. W., Baizabal-Aguirre, Víctor M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122595/ https://www.ncbi.nlm.nih.gov/pubmed/27933067 http://dx.doi.org/10.3389/fimmu.2016.00533

Ejemplares similares

Ability of Innate Defence Regulator Peptides IDR-1002, IDR-HH2 and IDR-1018 to Protect against Mycobacterium tuberculosis Infections in Animal Models
por: Rivas-Santiago, Bruno, et al.
Publicado: (2013)

Synthetic host defense peptide IDR-1002 reduces inflammation in Pseudomonas aeruginosa lung infection
por: Wuerth, Kelli C., et al.
Publicado: (2017)

Modulation of the immune response by the host defense peptide IDR-1002 in chicken hepatic cell culture
por: Sebők, Csilla, et al.
Publicado: (2023)

Characterization of Host Responses during Pseudomonas aeruginosa Acute Infection in the Lungs and Blood and after Treatment with the Synthetic Immunomodulatory Peptide IDR-1002
por: Wuerth, Kelli, et al.
Publicado: (2018)

Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts
por: Turner-Brannen, Emily, et al.
Publicado: (2011)

The Glycogen Synthase Kinase 3α and β Isoforms Differentially Regulates Interleukin-12p40 Expression in Endothelial Cells Stimulated with Peptidoglycan from Staphylococcus aureus
por: Cortés-Vieyra, Ricarda, et al.
Publicado: (2015)

Aromadendrin Inhibits Lipopolysaccharide-Induced Nuclear Translocation of NF-κB and Phosphorylation of JNK in RAW 264.7 Macrophage Cells
por: Lee, Jae-Won, et al.
Publicado: (2013)

Collaborative Action of Toll-Like and Nod-Like Receptors as Modulators of the Inflammatory Response to Pathogenic Bacteria
por: Oviedo-Boyso, Javier, et al.
Publicado: (2014)

Clofarabine induces ERK/MSK/CREB activation through inhibiting CD99 on Ewing sarcoma cells
por: Sevim, Handan, et al.
Publicado: (2021)

Melatonin Inhibits NF-κB/CREB/Runx2 Signaling and Alleviates Aortic Valve Calcification
por: Li, Shao-Jung, et al.
Publicado: (2022)

Synthetic Cationic Peptide IDR-1002 and Human Cathelicidin LL37 Modulate the Cell Innate Response but Differentially Impact PRRSV Replication in vitro
por: Levast, Benoît, et al.
Publicado: (2019)

IRF3 inhibits nuclear translocation of NF-κB to prevent viral inflammation
por: Popli, Sonam, et al.
Publicado: (2022)

Exclusive enteral nutrition protects against inflammatory bowel disease by inhibiting NF-κB activation through regulation of the p38/MSK1 pathway
por: Yu, Ting, et al.
Publicado: (2018)

TDP-43 Inhibits NF-κB Activity by Blocking p65 Nuclear Translocation
por: Zhu, Jingyan, et al.
Publicado: (2015)

Papaverine inhibits lipopolysaccharide-induced microglial activation by suppressing NF-κB signaling pathway
por: Dang, Yalong, et al.
Publicado: (2016)

Aloin Suppresses Lipopolysaccharide-Induced Inflammatory Response and Apoptosis by Inhibiting the Activation of NF-κB
por: Luo, Xuan, et al.
Publicado: (2018)

Shikonin Promotes Skin Cell Proliferation and Inhibits Nuclear Factor-κB Translocation via Proteasome Inhibition In Vitro
por: Yan, Yan, et al.
Publicado: (2015)

Toddalolactone Protects Lipopolysaccharide-Induced Sepsis and Attenuates Lipopolysaccharide-Induced Inflammatory Response by Modulating HMGB1-NF-κB Translocation
por: Ni, Jingyu, et al.
Publicado: (2020)

Dexmedetomidine Improves Anxiety-like Behaviors in Sleep-Deprived Mice by Inhibiting the p38/MSK1/NFκB Pathway and Reducing Inflammation and Oxidative Stress
por: Li, Jiangjing, et al.
Publicado: (2023)

Paeonol alleviates lipopolysaccharide-induced hepatocytes injury through alteration of mitochondrial function and NF-κB translocation
por: Xu, Shouzhu, et al.
Publicado: (2021)

MSK1 promotes cell proliferation and metastasis in uveal melanoma by phosphorylating CREB
por: Li, Jianchang, et al.
Publicado: (2019)

Blockade of NF-κB nuclear translocation results in the inhibition of the invasiveness of human gastric cancer cells
por: LI, ZHI-MIN, et al.
Publicado: (2013)

Vaccinia Virus Inhibits NF-κB-Dependent Gene Expression Downstream of p65 Translocation
por: Sumner, Rebecca P., et al.
Publicado: (2014)

Artemisinin Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Inhibiting NF-κB Pathway in Microglia Cells
por: Zhu, Cansheng, et al.
Publicado: (2012)

Formosanin C attenuates lipopolysaccharide-induced inflammation through nuclear factor-κB inhibition in macrophages
por: Yin, Limin, et al.
Publicado: (2021)

ETC-1002 Attenuates Porphyromonas gingivalis Lipopolysaccharide-Induced Inflammation in RAW264.7 Cells via the AMPK/NF-κB Pathway and Exerts Ameliorative Effects in Experimental Periodontitis in Mice
por: Li, Hongyan, et al.
Publicado: (2022)

Influence of the dopaminergic system, CREB, and transcription factor-κB on cocaine neurotoxicity
por: Planeta, C.S., et al.
Publicado: (2013)

4-Acetylantroquinonol B inhibits lipopolysaccharide-induced cytokine release and alleviates sepsis through of MAPK and NFκB suppression
por: Chang, Chien-Hsin, et al.
Publicado: (2018)

Icariside II inhibits lipopolysaccharide-induced inflammation and amyloid production in rat astrocytes by regulating IKK/IκB/NF-κB/BACE1 signaling pathway
por: Zheng, Yong, et al.
Publicado: (2019)

MicroRNA-21 inhibits lipopolysaccharide-induced acute lung injury by targeting nuclear factor-κB
por: Zhu, Wei-Dong, et al.
Publicado: (2018)

Inhibition of nuclear factor-κB signal by pyrrolidine dithiocarbamate alleviates lipopolysaccharide-induced acute lung injury
por: Yang, Hongfu, et al.
Publicado: (2017)

Docosahexaenoic Acid Inhibits UVB-Induced Activation of NF-κB and Expression of COX-2 and NOX-4 in HR-1 Hairless Mouse Skin by Blocking MSK1 Signaling
por: Rahman, Md. Mostafizur, et al.
Publicado: (2011)

Anti-Apoptotic Effect of Tax: An NF-κB Path or a CREB Way?
por: Saggioro, Daniela
Publicado: (2011)

IDR knowledge base for primary immunodeficiencies
por: Samarghitean, Crina, et al.
Publicado: (2007)

Impacts of PEGylation and Glycosylation on the Biological Properties of Host Defense Peptide IDR1018
por: Etayash, Hashem, et al.
Publicado: (2023)

Sulforaphene induces apoptosis and inhibits the invasion of esophageal cancer cells through MSK2/CREB/Bcl-2 and cadherin pathway in vivo and in vitro
por: Zhang, Chengjuan, et al.
Publicado: (2019)

To NFκB or not to NFκB: The Dilemma on How to Inhibit a Cancer Cell Fate Regulator
por: Sorriento, Daniela, et al.
Publicado: (2012)

Histone deacetylase 4 inhibits NF-κB activation by facilitating IκBα sumoylation
por: Yang, Qi, et al.
Publicado: (2021)

Synthetic Cationic Peptide IDR-1018 Modulates Human Macrophage Differentiation
por: Pena, Olga M., et al.
Publicado: (2013)

Tyrosol ameliorates lipopolysaccharide-induced ocular inflammation in rats via inhibition of nuclear factor (NF)-κB activation
por: SATO, Kazuaki, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_s2ie2qt7phj762d9796sf1i5qk