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Identificaiton of Novel Immunogenic Human Papillomavirus Type 16 E7-Specific Epitopes Restricted to HLA-A(*)33;03 for Cervical Cancer Immunotherapy

PURPOSE: To identify new immunogenic HLA-A(*)33;03-restricted epitopes from the human papillomavirus (HPV) 16 E7 protein for immunotherapy against cervical cancer. MATERIALS AND METHODS: We synthesized fourteen overlapping 15-amino acid peptides and measured intracellular interferon-γ (IFN-γ) produc...

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Detalles Bibliográficos
Autores principales: Kim, Sunghoon, Chung, Hye Won, Kong, Hoon Young, Lim, Jong-Baeck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122651/
https://www.ncbi.nlm.nih.gov/pubmed/27873494
http://dx.doi.org/10.3349/ymj.2017.58.1.43