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EGF Induced RET Inhibitor Resistance in CCDC6-RET Lung Cancer Cells

PURPOSE: Rearrangement of the proto-oncogene rearranged during transfection (RET) has been newly identified potential driver mutation in lung adenocarcinoma. Clinically available tyrosine kinase inhibitors (TKIs) target RET kinase activity, which suggests that patients with RET fusion genes may be t...

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Detalles Bibliográficos
Autores principales: Chang, Hyun, Sung, Ji Hea, Moon, Sung Ung, Kim, Han-Soo, Kim, Jin Won, Lee, Jong Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122657/
https://www.ncbi.nlm.nih.gov/pubmed/27873490
http://dx.doi.org/10.3349/ymj.2017.58.1.9