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TNF-α-Induced cPLA(2) Expression via NADPH Oxidase/Reactive Oxygen Species-Dependent NF-κB Cascade on Human Pulmonary Alveolar Epithelial Cells

Tumor necrosis factor-α (TNF-α) triggers activation of cytosolic phospholipase A(2) (cPLA(2)) and then enhancing the synthesis of prostaglandin (PG) in inflammatory diseases. However, the detailed mechanisms of TNF-α induced cPLA(2) expression were not fully defined in human pulmonary alveolar epith...

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Detalles Bibliográficos
Autores principales: Lin, Chih-Chung, Lin, Wei-Ning, Cho, Rou-Ling, Wang, Chen-yu, Hsiao, Li-Der, Yang, Chuen-Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122718/
https://www.ncbi.nlm.nih.gov/pubmed/27932980
http://dx.doi.org/10.3389/fphar.2016.00447