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Expression and purification of truncated diphtheria toxin, DT386, in Escherichia coli: An attempt for production of a new vaccine against diphtheria

The aim of this study was to produce a recombinant protein consisting of the catalytic and translocation domains of diphtheria toxin for its later application as a vaccine candidate against Corynebacterium diphtheria. To achieve this goal, at first, the amino acid sequence of DT386 was used for pred...

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Detalles Bibliográficos
Autores principales: Shafiee, Fatemeh, Rabbani, Mohammad, Behdani, Mahdi, Jahanian-Najafabadi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122833/
https://www.ncbi.nlm.nih.gov/pubmed/27920826
http://dx.doi.org/10.4103/1735-5362.192496